Advanced Gastrointestinal & Immune Testing
CDSA Stool Analysis offers insight into common gastrointestinal conditions
The Comprehensive Digestive Stool Analysis (CDSA)™ offers a comprehensive look at the overall health of the gastrointestinal (GI) tract. The CDSA™ is Genova’s historic evaluation of gastrointestinal function assessing a select set of stool biomarkers.
Evidence suggests that both local and systemic health issues may begin as imbalances in gastrointestinal function. Some of the consequences of imbalanced gastrointestinal health are:
- Irritable Bowel Syndrome (IBS)
- Altered GI immune function
- Bacterial/fungal overgrowth
- Chronic dysbiosis
This test helps determine the root cause of gastrointestinal issues using these markers:
- Putrefactive Short–Chain Fatty Acids
- Meat and Vegetable Fibers
- Fecal Fats
Gut Metabolic Markers
- Beneficial Short–Chain Fatty Acids (SCFA) with n–Butyrate
- SCFA distribution
- Fecal Lactoferrin
- Macroscopic (color, mucus)
- Occult Blood
Gut Microbiology Markers
- Beneficial Bacteria
- Additional Bacteria
Small intestine bacterial overgrowth (SIBO) is a common gastrointestinal disorder that often underlies chronic gastrointestinal symptoms of maldigestion and malabsorption, including bloating, gas, diarrhea, irregularity, and abdominal pain. This simple, non–invasive, gastrointestinal test detects bacterial overgrowth in the small intestine, often referred to as BOSI or SIBO.
Bacterial overgrowth can inhibit nutrient absorption and lead to the following serious health problems:
- Altered intestinal permeability (leaky gut)
- Carbohydrate intolerance
- Malnutrition and weight loss
- Chronic Fatigue Syndrome
Causes of small intestine bacterial overgrowth (SIBO/BOSI):
- Crohn’s Disease
- Radiation Damage
The Bacterial Overgrowth of the Small Intestine Breath Test (SIBO/BOSI) is appropriate for patients who demonstrate:
- Irritable Bowel Syndrome (IBS), the most commonly diagnosed gastrointestinal disorder, affecting 20% of the general population. The SIBO test aids in identifying the actual cause of IBS. Studies suggest that as many as 50-75% of patients with IBS have SIBO/BOSI, as demonstrated by hydrogen breath testing.
- Unexplained abdominal symptoms, especially gas and bloating.
- The inability to tolerate sweet or starchy foods, fiber, or friendly flora supplements.
CYREX Testing for Immune Conditions
Multiple Autoimmune Reactivity Screen
- A test recommended for patients concerned with autoimmune disorders. It has predictive antibodies, some of which that appear up to 10 years before the clinical onset of disease.
Wheat/Gluten Proteome Reactivity & Autoimmunity
- A test recommended for patients with multiple symptom complaints including CFS, Fibromyalgia or depression. It measures antibody production against 9 wheat proteins and peptides and 3 essential structure enzymes.
Gluten-Associated Cross-Reactive Foods & Food Sensitivity
- A test recommended for patients who have gut dysbiosis and have been non responsive to gluten-free diet. It is to identify additional dietary proteins to which non-Celiac patient is sensitized.
Chemical Immune Reactivity Screen
- A test recommended for patients who have an increased chemical sensitivity or intolerance. This test includes substances such as BPA, Parabens, Mercury, Aflatoxins, Benzene, and heavy metals.
Multiple Food Reactivity Screen
- A comprehensive food immune reactivity screen that includes dairy, beans, legumes, nuts, seeds, fruit, fish, seafood, meats, eggs, grains, herbs, spices, gums and additives.
COLOGAURD Colon Cancer Home Screening
How does Cologuard work?
Every day the lining of your colon naturally sheds cells. If you have cancer or precancer in your colon, abnormal cells shed into the colon – along with normal cells – where they are picked up by stool as it passes through.
Cologuard uses advanced stool DNA technology to find elevated levels of altered DNA and/or hemoglobin in these abnormal cells, which could be associated with cancer or precancer.
How is a sample collected?
The Cologuard Collection Kit is easy to use, and it’s shipped directly to your home. You collect a single stool sample using this kit, then send it to Exact Sciences Labs via prepaid UPS shipping or pick-up. We provide the result back to your doctor, who will contact you to discuss next steps.
What are the risks and precautions associated with Cologuard?
Cologuard is not for everyone. It is not a replacement for diagnostic or surveillance colonoscopy in high-risk individuals. It may not be right for you if:
- You have a personal history of colon cancer, polyps, or other related cancers.
- You have a family history of colon cancer.
- You have had a positive result for another screening method in the last six months.
- You have been diagnosed with a condition that places you at high risk for colon cancer. These include but are not limited to: Inflammatory Bowel Disease, Chronic ulcerative colitis, Crohn’s disease, Familial adenomatous polyposis.
- You have been diagnosed with a relevant cancer syndrome passed on from your family, such as Hereditary non-polyposis colorectal cancer syndrome, Peutz-Jeghers Syndrome, MYH-Associated Polyposis, Gardner’s syndrome, Turcot’s (or Crail’s) syndrome, Cowden’s syndrome, Juvenile Polyposis, Cronkhite-Canada syndrome, Neurofibromatosis, or Familial Hyperplastic Polyposis.
- Results should be interpreted with caution for individuals over age 75, as the rate of false positives increases with age.
Cologuard may produce false positive or false negative results.
- A false positive occurs when Cologuard produces a positive result, even though a colonoscopy will not find cancer or precancer. Any positive result should be followed by diagnostic colonoscopy.
- A false negative occurs when Cologuard does not detect colon cancer or precancer even when a colonoscopy identifies the positive result. Following a negative result, patients should continue participating in a screening program at an interval and with a method appropriate for the individual patient.
Cologuard performance when used for repeat testing has not been evaluated or established.